Buy cheap Zerit

Zerit (Stavudine) is a nucleoside analog reverse transcriptase inhibitor active against HIV.
Zerit (Stavudine) is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Zerit (Stavudine) triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it.

Simultaneous use of AZT is not recommended, as it can inhibit the intracellular phosphorylation of Zerit (Stavudine). Other anti-HIV drugs do not possess this property.

The main severe adverse effect is peripheral neuropathy, which can be corrected by reducing dosage. Zerit (Stavudine) has been shown in laboratory test to be genotoxic, but with clinical doses its carcinogenic effects are non-existent. It is also one of the most likely antiviral drugs to cause lipodystrophy.

It is still used as first choice in first line therapy in resource poor settings such as in India. Only in case of development of peripheral neuropathy or pregnancy is it changed to the next choice - Zidovudine.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.